The eye area is one of the most delicate regions of the face. Constantly exposed to environmental stressors and natural facial movements, it tends to age more quickly compared to other areas. Fine lines, sagging, under-eye bags, and dark circles often appear earlier here, making the eyes a key focus in anti-aging treatments. Because of its unique structure, the eye area requires a specific and targeted treatment to restore vitality, firmness, and radiance.
How the Eye Area Ages
Aging around the eyes is influenced by both structural and functional changes:
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Eyebrow descent: The downward shift of the brow accentuates sagging of the upper eyelid.
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Collagen and elastin loss: Leads to wrinkles, commonly known as “crow’s feet.”
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Under-eye sagging: Fat tissue relocation contributes to puffy bags under the eyes.
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Skin thinning & poor circulation: Sluggish lymphatic and venous flow causes fluid retention. Combined with melanin and oxidized hemoglobin buildup, this results in dark eye circles.
These changes create a tired and aged appearance, even in otherwise youthful faces.
The Science of Nucleofill Eyes
Nucleofill Eyes is a cutting-edge treatment designed specifically for the periocular region. It contains highly purified polynucleotides that activate deep-level skin bio-regeneration, working from adipose and bone tissue up to the dermis.
Its multi-action benefits include:
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Hydration: Restores moisture balance in the delicate eye skin.
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Antioxidant protection: Shields cells from oxidative stress.
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Fibroblast stimulation: Increases both the number and activity of fibroblasts, encouraging continuous renewal of dermal components.
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Cellular metabolism support: Helps maintain healthy physiological functions.
The result? Firmer, smoother, and brighter skin around the eyes.
Indications for Nucleofill Eyes
This treatment is recommended for patients seeking:
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Reduction of eye bags
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Smoothing of periocular wrinkles
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Re-densification of the dermo-epidermal tissue
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Bio-restructuration of deeper tissues
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Improvement of fine lines without fillers
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Supportive care for pre- and post-surgical procedures
Techniques Used in Nucleofill Eyes
There are two main application techniques, tailored to different treatment depths:
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Pomfus Technique
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Uses micro-wheal injections at a superficial level.
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Provides bio-restructuring of surface tissues and smooths fine wrinkles.
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Linear Retrograde Technique
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Uses a cannula in the hypodermis with a fanning method.
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Targets deep tissue bio-restructuring for more advanced concerns like eye bags.
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Treatment Protocol
For optimal results, the recommended protocol is:
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2 sessions spaced 2 weeks apart
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Followed by 2 sessions spaced 3 weeks apart
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Maintenance treatment every 3 months
This structured approach ensures both immediate improvements and long-term regenerative effects.
Nucleofill Soft Plus for Eyebags
In addition to Nucleofill Eyes, Nucleofill Soft Plus offers enhanced results for under-eye bags, using either the Pomfus or Linear technique depending on the depth of treatment required.
The Bottom Line
The eyes are often the first feature to show signs of aging—but with targeted solutions like Nucleofill Eyes, it’s possible to restore youthfulness and vitality to this delicate area. By addressing hydration, fibroblast renewal, and tissue restructuring, Nucleofill Eyes offers a holistic, non-filler approach to rejuvenating the periocular region.

Nucleofil Soft Plus

Pomfus Technique

Linear Technique

Eyebags